Brennan (Emily Deschanel) and Booth's (David Boreanaz) relationship will be affected as the couple struggles with a big loss in their family on the next episode of "Bones" season 12.

In the previous episode titled "The Scare in the Score," Brennan's father Max Keenan (Ryan O'Neal) suddenly died after telling her a heartwarming story about his dream where the rest of their family are having a good time together. This will obviously devastate Brennan, since Max had been an important part of her life.

But the synopsis for the upcoming episode called "The Grief and the Girl" reveals that Max's death will have a huge impact on Brennan's relationship with her husband Booth. According to the synopsis, the two will fall apart after they deal with their sorrow through different ways.

Several photos from the upcoming episode show that Booth is already working on a new case with Aubrey (John Boyd) after his father-in-law's death.

On the other hand, the trailer also reveals that Brennan will deal with her loss by herself. Booth will try to reach out to her, but she will decide to keep quiet and shut him out so she can grieve for her father.

The trailer also reveals that Brennan's ex-boyfriend Sully (Eddie McClintock) will drop her a visit to comfort her. Could it result to a further rift between the couple?

Aside from McClinton, the episode will feature other guest stars such as Eugene Byrd as Dr. Clark Edison, Miranda Frigon as Gilda Sandling, Dale Raoul as Gretchen Crockett, Lindsey Haun as Tess Abbott, A Leslie Kies as Kathleen Tobine, Tom Degnan as Adam Hitchcock, Wolfgang Bodison as Doug Patton, Greg Evigan as Rick Tobine, as well as Wylie Small as Lucy Andreassen.

FOX will air the next episode of "Bones" season 12 on Tuesday, Feb. 21, at 9 p.m.